A new synthesis of N-substituted-1,2,3,4-tetrahydro-4-phenylisoquinolin-3-ones

Article abstract of DOI:10.1080/00397919308011228

1,2,3,4-Tetrahydro-4-phenylisoquinolin-3-ones 3 are obtained from appropriate N,N-disubstituted phenylacetamides 1, using lead tetraacetate (LTA) as oxidant and Lewis or proton acids as cyclizing agents. The methods for this conversion could be one stage (method B or C), or two stages (method A). The latter method was particularly developed to explain the mechanism of the reaction.

Full text of DOI:10.1080/00397919308011228

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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A New Synthesis of N-
Substituted-1,2,3,4-
tetrahydro-4-
phenylisoquinolin-3-ones
Necdet Coskun a & Dogan Sümengen a
a Department of Chemistry, Uludag University, Bursa,
Turkey
Version of record first published: 23 Sep 2006
To cite this article: Necdet Coskun & Dogan Sümengen (1993): A New Synthesis
of N-Substituted-1,2,3,4-tetrahydro-4-phenylisoquinolin-3-ones, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 23:10, 1393-1402
To link to this article: http://dx.doi.org/10.1080/00397919308011228
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