Asymmetric Synthesis XXIV. Benzoquinolizidine Analogues of Podophyllotoxin via CN(R,S) Method.

DOI: 10.1016/S0040-4039(00)74362-0

Source and publish data:

Tetrahedron Letters p. 2489 - 2492 (1991)

Update date:2022-08-05

Topics:

Authors:

Lienard, Philippe

Royer, Jacques

Quirion, Jean-Charles

Husson, Henri-Philippe

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Article abstract of DOI:10.1016/S0040-4039(00)74362-0

The alkylation of 2-cyano-6-phenyloxazolopiperidin synthon 1 gave after reduction, the optically active pivotal amine 4.Bischler-Napieralski reaction of different aryl amides derived from 4 furnished the podophyllotoxin analogues 7, 8, and 9 after NaBH4 r

Full text of DOI:10.1016/S0040-4039(00)74362-0

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