Synthesis and anti-hypertensive activity of novel sulphadimidine derivatives

Article abstract of DOI:10.1007/s00044-011-9935-3

A series of novel sulphadimidine derivatives has been synthesized via coupling of sulphadimidine diazonium salt with N-substituted anilines in acetic acid and subjected to evaluate their antihypertensive activity. All the synthesized compounds have similar effects and non-significantly different than the standard drug (Prazosin) and control groups. All newly synthesized dyes were characterized by elemental analyses and spectral data (IR, 1H-NMR, and MS). Springer Science+Business Media, LLC 2011.