N-metallo imines: A new approach to α-amino alcohols from aldehydes

DOI: 10.1016/0040-4039(91)80664-R

Source and publish data:

Tetrahedron Letters p. 2967 - 2970 (1991)

Update date:2022-08-05

Topics:

Authors:

Cainelli

Giacomini

Mezzina Mezzina

Panunzio

Zarantonello

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Article abstract of DOI:10.1016/0040-4039(91)80664-R

The addition of lithium alkyls or Grignard reagents to the in situ generated O-protected α-hydroxy-N-trimethylsilylimines proceeds in good yields and highly stereocontrolled manner to produce 1,2-aminols.

Full text of DOI:10.1016/0040-4039(91)80664-R

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