Synthesis of Organofluorine Building Blocks. 3. An Electrochemical Preparation and Reaction of Dimethyl 2,3-Bis(2,2,2-trifluoroethyl)succinate

Article abstract of DOI:10.1021/jo00265a029

Dimethyl 2,3-bis(2,2,2-trifluoroethyl)succinate (2) was prepared in a 50percent yield by electrochemical oxidation of trifluoroacetic acid (TFA) and methyl acrylate.Electrolysis was conducted in an MeCN-H2O (7:1)-NaOH (0.1 equiv to TFA) system by using pl