Synthesis of new indolactam analogues by microbial conversion

DOI: 10.1016/S0040-4020(01)80978-9

Source and publish data:

Tetrahedron p. 5453 - 5462 (1991)

Update date:2022-08-04

Topics:

Authors:

Kajiyama, Shin-Ichiro

Irie, Kazuhiro

Kido, Takae

Koshimizu, Koichi

Hayashi, Hideo

Arai, Motoo

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Article abstract of DOI:10.1016/S0040-4020(01)80978-9

Ten indolactam congeners with L-Ala, Abu, γ,δ-Δ-Nva, Nva, Nle, tert-Leu, Leu, Ile, allo-Ile. Phg instead ofL-Val in (-)-indolactam-Val, were synthesized from their seco-compounds (N-methyl-L-amino acidyl-L-tryptophonol) by microbial conversion.

Full text of DOI:10.1016/S0040-4020(01)80978-9

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Product name:N-methyl-L-phenyl-Gly-L-Trp-ol

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