Tandem Chiral Cu(II) Phosphate-Catalyzed Deoxygenation of Nitrones/Enantioselective Povarov Reaction with Enecarbamates

DOI: 10.1002/ejoc.201900547

Source and publish data:

European Journal of Organic Chemistry p. 5151 - 5155 (2019)

Update date:2022-08-05

Topics: Enantioselective Povarov Reaction

Authors:

Gelis, Coralie

Levitre, Guillaume

Guérineau, Vincent

Touboul, David

Neuville, Luc

Masson, Géraldine

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1002/ejoc.201900547

A new catalytic enantioselective tandem deoxygenation/aza-Diels-Alder reaction of nitrones with enecarbamates was serendipitously discovered in the presence of chiral copper(II) diphosphate complexes. This process affords a wide range of 4-aminotetrahydroquinolines in respectable yields under mild conditions with good to excellent ee values.

Full text of DOI:10.1002/ejoc.201900547

Products guided by the article

Product name:C₁₃H₁₅NO₂

Cas No:1362048-96-1

R&D Labs maybe for 1362048-96-1

Zhejiang Sucon Silicone Co.,Ltd

Contact:+86-575-88046692

Address:Qisheng Rd., Paojiang Industrial Zone, Shaoxing, Zhejiang, China.
Shanghai Run-Biotech Co., Ltd.

website:http://www.run-biotech.com

Contact:+86-21-31576854/57171705 / 57171706

Address:second floor, building 3, No.999, jiangyue Road, minghang District, Shanghai, China
Geen Chemical Technology Co., Ltd

Contact:86-769-21660847

Address:1408, Yingfeng Commercial Center, Nancheng District
Shandong united-rising pharmaceutical cooperation.,ltd.

Contact:008653187965009

Address:171No., Jing5 Road, Shizhong District, Jinan, China
Qingdao S. H. Huanyu Imp. & Exp. Co., Ltd.

Contact:86-532-88250866

Address:Room 615, World Trade Centre Building B, Hongkong Middle Roda 6#, Qingdao, Shandong, China

Relevant to this article

Synthesis, evaluation and docking studies on 3-alkoxy-4-methanesulfonamido acetophenone derivatives as non ulcerogenic anti-inflammatory agents

Doi:10.1016/j.ejmech.2012.01.018
(2012)
Regioselective synthesis of trifluoromethylated 3-(pyrazolyl)indoles on the basis of 6-(trifluoromethyl)comanic acid

Doi:10.1016/j.jfluchem.2011.12.008
(2012)
Azidomercurations of alkenes: Mercury-promoted Schmidt reactions

Doi:10.1021/jo001181q
(2000)
Synthesis, Characterization, and Crystal Structures of Oxidovanadium(V) Complexes Derived from 2-Chloro-N'-(3,5-dichloro-2-hydroxybenzylidene)benzohydrazide with Antimicrobial Activity

Doi:10.1134/S1070328419040109
(2019)
Synthesis and in vitro urease inhibitory activity of benzohydrazide derivatives, in silico and kinetic studies

Doi:10.1016/j.bioorg.2018.09.036
(2019)
[4+2] Cyclohexane ring formation by a tandem of a free radical alkylation of a non-activated δ-carbon atom and intramolecular carbanion cycloalkylation

Doi:10.1055/s-2004-829115
(2004)

Article Doi