β-Keto-δ-valerolactone: Synthesis and use as methylvinylketone anion equivalent in michael additions

DOI: 10.1016/0040-4039(91)80689-4

Source and publish data:

Tetrahedron Letters p. 3063 - 3066 (1991)

Update date:2022-08-03

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Authors:

D'Angelo, Jean

Gomez-Pardo, Domingo

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Article abstract of DOI:10.1016/0040-4039(91)80689-4

β-Keto-δ-valerolactone 11 was prepared from 3-butyn-l-ol 6 in 5 steps (50 % overall yield). This lactone was added to Michael acceptors 13, 17, 19 and 25, giving adducts 14, 18, 20 and 26 respectively.

Full text of DOI:10.1016/0040-4039(91)80689-4

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