HIGHLY CONVERGENT APPROACH TO THE SYNTHESIS OF THE EPOXY-AMIDE FRAGMENT OF THE AZINOMYCINS

DOI: 10.1016/S0040-4039(00)79381-6

Source and publish data:

Tetrahedron Letters p. 3807 - 3810 (1991)

Update date:2022-08-03

Topics:

Authors:

Moran, Edmund J.

Armstrong, Robert W.

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Article abstract of DOI:10.1016/S0040-4039(00)79381-6

An efficient synthesis of the α-acyl amide fragment of the azinomycin antibiotics has been accomplished using the Passerini three-component condensation.Good diastereoselectivity was observed for a variety of isocyanide precursors.

Full text of DOI:10.1016/S0040-4039(00)79381-6

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