Phosphorus, Sulfur and Silicon and the Related Elements p. 555 - 563 (2012)
Update date:2022-09-26
Topics:
Abdel-Fattah, Azza M.
Attaby, Fawzy A.
Benzothiophene-2-carbaldehyde 1 reacted with 2-cyanoethanethioamide 2 in 1:2 molar ratios to give the corresponding 6-amino-4-(benzo[b]thiophen-2-yl)-2- thioxo-1, 2-dihydropyridine-3,5-dicarbonitrile 6. The synthetic potentiality of compound 6 was investigated via its reaction with active halogen-containing reagents to afford the corresponding thieno[2,3-b]pyridine derivatives 11a,b, 14, 16, and 19. Also, compound 6 reacted with hydrazine hydrate to give the pyrazolo[3,4-b]pyridine derivative 21. Compound 21 condensed with 4-(2-thienyl)benzaldehyde to afford pyrazolo[3,4-b]pyridine derivative 23. Structural elucidation of all the newly synthesized heterocyclic compounds was based on elemental analyses, IR, 1H NMR, and mass spectra. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.
View MoreChangzhou naidechemical Co.Ltd
Contact:+86-519-82589807
Address:NO.25,Houyang street,Jintan,Changzhou City
Contact:+86-511-88790000
Address:338 North Yushan Rd, Zhenjiang, Jiangsu 212016
ShenZhen InnoSyn Biotech Co.,Ltd
website:http://www.innosyns.com
Contact:+86-755-28351685
Address:Floor 5 & 6, Building A1, HAIKEXING Strategic Innovative Industrial Park, 16 BaoShan Road, PingShan District
Zibo Jujin Chemical Industry Co., Ltd.(Dongming Jujin Chemical Industry Co., Ltd. )
Contact:+86-533-2975022
Address:No.99 Shanquan Road, Zhangdian District
Shanxi Tongji Pharmaceuticals Co., Ltd.
Contact:+86-359-3024784
Address:Xikuang South Road, Ruicheng County , Shanxi
Doi:10.1016/j.tetlet.2003.10.183
(2004)Doi:10.1039/a801718b
(1998)Doi:10.1002/hlca.19680510717
(1968)Doi:10.1002/anie.201406959
(2014)Doi:10.1039/a801294f
(1998)Doi:10.1021/ja980513u
(1998)