Phosphorus, Sulfur and Silicon and the Related Elements p. 555 - 563 (2012)
Update date:2022-09-26
Topics:
Abdel-Fattah, Azza M.
Attaby, Fawzy A.
Benzothiophene-2-carbaldehyde 1 reacted with 2-cyanoethanethioamide 2 in 1:2 molar ratios to give the corresponding 6-amino-4-(benzo[b]thiophen-2-yl)-2- thioxo-1, 2-dihydropyridine-3,5-dicarbonitrile 6. The synthetic potentiality of compound 6 was investigated via its reaction with active halogen-containing reagents to afford the corresponding thieno[2,3-b]pyridine derivatives 11a,b, 14, 16, and 19. Also, compound 6 reacted with hydrazine hydrate to give the pyrazolo[3,4-b]pyridine derivative 21. Compound 21 condensed with 4-(2-thienyl)benzaldehyde to afford pyrazolo[3,4-b]pyridine derivative 23. Structural elucidation of all the newly synthesized heterocyclic compounds was based on elemental analyses, IR, 1H NMR, and mass spectra. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.
View MoreLianyungang Yunbo Chemical Co.,Ltd.
Contact:518-81066110
Address:B907,Dongsheng"Mingdu Square,21-2 East Chaoyang Road,Xinpu,(sale department)
Jiangsu King Road New Materials Co., Ltd.
website:http://www.jskingroad.com
Contact:0519-85720726 0519-85720721 13584535752
Address:No.1,Weihua Road,Xinbei District,Changzhou City,Jiangsu Province
Zhejiang Golden-Shell Pharmaceutical Co.,Ltd.
Contact:+86-576-87501888 / 87501988
Address:No.89 Zhongxing Road. Li'ao, Yuhuan, Zhejiang, China
Contact:+86-535-8888888
Address:No.161 Haishi Rd.
Shanghai birch chemical technology co.,ltd
Contact:+86-21-54096810
Address:No.2588,Jungong Road,Shanghai,China
Doi:10.1016/j.tetlet.2003.10.183
(2004)Doi:10.1039/a801718b
(1998)Doi:10.1002/hlca.19680510717
(1968)Doi:10.1002/anie.201406959
(2014)Doi:10.1039/a801294f
(1998)Doi:10.1021/ja980513u
(1998)