Chemical Communications p. 4453 - 4455 (2012)
Update date:2022-09-26
Topics:
Ge, Jingyan
Cheng, Xiamin
Tan, Lay Pheng
Yao, Shao Q.
The multi-component Ugi reaction has been employed to assemble a small library of affinity-based probes (AfBPs) that target potential protein tyrosine phosphatases. The probes showed good labelling of PTP1B and MptpB, and were subsequently used to label endogenous PTP1B in MCF-7 cell lysates.
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