An expedient synthesis of the proposed biosynthetic precursor of the oxepine natural product, janoxepin

DOI: 10.1016/j.tetlet.2012.03.025

Source and publish data:

Tetrahedron Letters p. 2533 - 2536 (2012)

Update date:2022-07-30

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Authors:

Doveston, Richard G.

Taylor, Richard J.K.

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Article abstract of DOI:10.1016/j.tetlet.2012.03.025

An efficient synthetic route to the putative biosynthetic intermediate of the anti-plasmodial natural product janoxepin is described. This novel enamine-containing pyrazino[2,1-b]quinazoline-3,6-dione, and its synthetic precursors, should be of value in s

Full text of DOI:10.1016/j.tetlet.2012.03.025

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