Base-Promoted Synthesis of Quinoline-4(1H)-thiones from o-Alkynylanilines and Aroyl Isothiocyanates

DOI: 10.1021/acs.orglett.7b02993

Source and publish data:

Organic Letters p. 6128 - 6131 (2017)

Update date:2022-09-26

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Authors:

Modi, Anju

Sau, Prasenjit

Patel, Bhisma K.

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Article abstract of DOI:10.1021/acs.orglett.7b02993

A base-promoted synthesis of quinoline-4(1H)-thiones has been accomplished from the in situ generated o-alkynylthiourea, obtained by reacting o-alkynylanilines with aroyl/acyl isothiocyanates. A 6-exo-dig S-cyclization of the in situ generated thiourea is

Full text of DOI:10.1021/acs.orglett.7b02993

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