Erratum: Catalytic enantioselective protonation of nitronates utilizing an organocatalyst chiral only at sulfur (Journal of the American Chemical Society (2012) 134 (9058-9061)DOI: 10.1021/ja3026196)

Full text of DOI:10.1021/ja306016b

Addition/Correction
pubs.acs.org/JACS
Correction to Catalytic Enantioselective Protonation of Nitronates
Utilizing an Organocatalyst Chiral Only at Sulfur
Kyle L. Kimmel, Jimmie D. Weaver, Melissa Lee, and Jonathan A. Ellman*
J. Am. Chem. Soc. 2012, 134, 9058−9061. DOI: 10.1021/ja3026196
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* Supporting Information
Page 9060. We recently established that Scheme 5 in the original
manuscript contains incorrect structures. The corrected
Scheme 5. Corrected Synthesis of α,γ-Disubstituted γ-Lactams
structures as well as an additional transformation to provide
the desired lactams 12 are now provided. α-Carboxy γ-lactams 10
and γ-lactams 11 are now correctly depicted as the N-hydroxy
derivatives. Reduction of the N-hydroxy lactams 11 to the desired
lactams 12 is accomplished in high yield by treatment with TiCl3
under mild conditions. Full experimental details, analytical data,
and spectra for 12a−c are provided in the corrected Supporting
Information.
ASSOCIATED CONTENT
* Supporting Information
■
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Corrected structures are provided in the procedures to prepare
10 and 11 and on their spectra and HPLC traces. Full
experimental procedures, analytical data, and spectra are
provided for the additional transformation to prepare 12. This
material is available free of charge via the Internet at http://pubs.
acs.org.
Published: July 3, 2012
© 2012 American Chemical Society
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dx.doi.org/10.1021/ja306016b | J. Am. Chem. Soc. 2012, 134, 11828−11828