Reaction of 1-bromo-1,2-dienes with alkylcuprates as a regio- and stereo-selective route to acetylenic or allenic compounds

Article abstract of DOI:10.1016/0022-328X(91)80179-N

Alkylcuprates react with 1-bromo-1,2-dienes to give allenic and/or acetylenic products.The selectivity of the crosscoupling is markedly dependent on the nature of the copper reagent, which plays a prominent role in determining both the regio- and the stereo-chemistry.The preparative aspects of these copper-induced reactions are discussed and their possible mechanism discussed.