N-Modified Analogues of Cocaine: Synthesis and Inhibition of Binding to the Cocaine Receptor

DOI: 10.1021/jm00079a018

Source and publish data:

Journal of Medicinal Chemistry p. 141 - 144 (1992)

Update date:2022-08-05

Topics:

Authors:

Abraham, Philip

Pitner, J. Bruce

Lewin, Anita H.

Boja, John W.

Kuhar, Michael J.

Carroll, F. Ivy

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00079a018

Cocaine methiodide (2), N-norcocaine (1b), N-benzyl-N-norcocaine (1c), and N-nor-N-acetylcocaine (1d) were synthesized and evaluated for their ability to inhibit binding of <3H>-3β-(4-fluorophenyl)tropane-2β-carboxylic acid methyl ester (WIN 35,428) to th

Full text of DOI:10.1021/jm00079a018

Products guided by the article

Product name:(+/-)-6-methyl-6-azabicyclo<3.2.1>octan-3β-ol benzoate

Cas No:137668-44-1

R&D Labs maybe for 137668-44-1

Shanghai Gsyn Chemical Co.,Ltd.

Contact:86-021-67158290

Address:86-021-67158291
Chongqing maohuan Chemicals Co., Ltd

website:http://www.bschem.com

Contact:+86 13996103726

Address:Chongqing Nan'an District Tu Town
HENAN NEW BLUE CHEMICAL CO.,LTD

website:http://www.newbluechem.com

Contact:86-371-55170693/55170694

Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China
Taizhou Crene Biotechnology co.ltd

Contact:86-576-88813233 88205808

Address:Economic Developed Zone of Taizhou Zhejiang China
Zhejiang Kangfeng Chemical Co.,LTD.

Contact:+86-579-86709687

Address:Xueshizhai Industrial Zone, Weishan Town,Dongyang City, Zhejiang Province ,China

Relevant to this article

Highly stereoselective 7-endo-trig /ring contraction cascade to construct pyrrolo[1,2- a ]quinoline derivatives

Doi:10.1021/ol100220c
(2010)
A novel nitrogen-containing compound with D-π-A structure: Theoretical and experimental study

Doi:10.1139/cjc-2013-0437
(2014)
Fe-catalyzed multicomponent reactions: The regioselective alkoxy allylation of activated olefins and its application in sequential Fe catalysis

Doi:10.1002/chem.201103009
(2012)
Synthesis, characterization and molecular structure of ruthenium complexes containing imidazole-2-carboxylic acid derivatives

Doi:10.1016/j.poly.2012.04.020
(2012)
Synthetic, structural, and physical investigations of the large linear and branched oligogermanes Ph₃GeGePh₂GePh₂GePh ₂H, Ge₅Ph₁₂, and (Ph₃Ge) ₄Ge

Doi:10.1021/om300385n
(2012)
Ruthenium-catalyzed highly regioselective cyclization of ketoximes with alkynes by C-H bond activation: A practical route to synthesize substituted isoquinolines

Doi:10.1021/ol301091z
(2012)

Article Doi