N-Modified Analogues of Cocaine: Synthesis and Inhibition of Binding to the Cocaine Receptor

DOI: 10.1021/jm00079a018

Source and publish data:

Journal of Medicinal Chemistry p. 141 - 144 (1992)

Update date:2022-08-05

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Authors:

Abraham, Philip

Pitner, J. Bruce

Lewin, Anita H.

Boja, John W.

Kuhar, Michael J.

Carroll, F. Ivy

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Article abstract of DOI:10.1021/jm00079a018

Cocaine methiodide (2), N-norcocaine (1b), N-benzyl-N-norcocaine (1c), and N-nor-N-acetylcocaine (1d) were synthesized and evaluated for their ability to inhibit binding of <3H>-3β-(4-fluorophenyl)tropane-2β-carboxylic acid methyl ester (WIN 35,428) to th

Full text of DOI:10.1021/jm00079a018

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