N-Modified Analogues of Cocaine: Synthesis and Inhibition of Binding to the Cocaine Receptor

DOI: 10.1021/jm00079a018

Source and publish data:

Journal of Medicinal Chemistry p. 141 - 144 (1992)

Update date:2022-08-05

Topics:

Authors:

Abraham, Philip

Pitner, J. Bruce

Lewin, Anita H.

Boja, John W.

Kuhar, Michael J.

Carroll, F. Ivy

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00079a018

Cocaine methiodide (2), N-norcocaine (1b), N-benzyl-N-norcocaine (1c), and N-nor-N-acetylcocaine (1d) were synthesized and evaluated for their ability to inhibit binding of <3H>-3β-(4-fluorophenyl)tropane-2β-carboxylic acid methyl ester (WIN 35,428) to th

Full text of DOI:10.1021/jm00079a018

Products guided by the article

Product name:(+/-)-6-methyl-6-azabicyclo<3.2.1>octan-3β-ol benzoate

Cas No:137668-44-1

R&D Labs maybe for 137668-44-1

Yantai Derun Liquid Crystal Materials Co. Ltd.

website:http://www.ytderun.com

Contact:86-535-6300169

Address:ROOM 90, XIANGFU STREET, FUSHAN NEW-HIGH-TECH IDUSTRY ZONE, YANTAI
enantiotech corporation ltd

Contact:+86-0760-85282375

Address:zhongjing road,zhongshan torch hi-tech industrial development zone
Sigma-Aldrich Chemie GmbH

website:http://www.sigmaaldrich.com

Contact:800 558-9160

Address:Industriestrasse 25CH-9471 Buchs SGSwitzerland
Tianjin Tongde Biological Technology Co., Ltd.

Contact:86-22-23309138

Address:Room 402, bulidingE3 Detection certification park, XiQingDistrict, Tianjin City
Chongqing Rong＆Quan Pharmaceutical Technology Co. , Ltd.

Contact:86-023-65268721

Address:No. 7, Manshanhong Village, Pingdingshan, Shapingba District, Chongqing Province, China

Relevant to this article

Highly stereoselective 7-endo-trig /ring contraction cascade to construct pyrrolo[1,2- a ]quinoline derivatives

Doi:10.1021/ol100220c
(2010)
A novel nitrogen-containing compound with D-π-A structure: Theoretical and experimental study

Doi:10.1139/cjc-2013-0437
(2014)
Fe-catalyzed multicomponent reactions: The regioselective alkoxy allylation of activated olefins and its application in sequential Fe catalysis

Doi:10.1002/chem.201103009
(2012)
Synthesis, characterization and molecular structure of ruthenium complexes containing imidazole-2-carboxylic acid derivatives

Doi:10.1016/j.poly.2012.04.020
(2012)
Synthetic, structural, and physical investigations of the large linear and branched oligogermanes Ph₃GeGePh₂GePh₂GePh ₂H, Ge₅Ph₁₂, and (Ph₃Ge) ₄Ge

Doi:10.1021/om300385n
(2012)
Ruthenium-catalyzed highly regioselective cyclization of ketoximes with alkynes by C-H bond activation: A practical route to synthesize substituted isoquinolines

Doi:10.1021/ol301091z
(2012)

Article Doi