Organic Letters p. 5813 - 5816 (2019)
Update date:2022-08-05
Topics:
Kawamoto, Yuichiro
Kobayashi, Toyoharu
Ito, Hisanaka
The first enantioselective total synthesis of diocollettines A was accomplished in only six steps from a known compound. A short and practical synthetic route was disclosed, featuring an intensive investigation of the stereoselective aldol reaction as a key step using an easily prepared aldehyde moiety and an enone derivative. The synthetic scheme also includes the efficient stereocontrolled construction of the tricyclic skeleton of diocollettines A by intramolecular acetal formation, stereoselective dihydroxylation, and intramolecular ether cyclization.
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Doi:10.1016/S0040-4039(00)92269-X
(1991)Doi:10.1016/S0040-4020(01)96162-9
(1991)Doi:10.1016/0022-1902(61)80382-5
(1961)Doi:10.1016/j.tetlet.2012.04.032
(2012)Doi:10.1021/jo300840x
(2012)Doi:10.1021/ol301085v
(2012)