Generation and Alkylation of Carbanions α to the Nitrogen of Amines by a New Metalation Procedure

DOI: 10.1021/jo00029a001

Source and publish data:

Journal of Organic Chemistry p. 793 - 794 (1992)

Update date:2022-09-26

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Authors:

Murakami, Masahiro

Hayashi, Minoru

Ito, Yoshihiko

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Article abstract of DOI:10.1021/jo00029a001

Treatment of a tertiary amine having a pendent o-iodobenzyl group on nitrogen with SmI2 generates α-amino organosamarium, which reacts with electrophiles giving the corresponding C-C bond formation products in good yield.

Full text of DOI:10.1021/jo00029a001

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