A Novel Approach to the Synthesis of Enediynes

DOI: 10.1016/0040-4039(91)80759-Y

Source and publish data:

Tetrahedron Letters p. 6085 - 6088 (1991)

Update date:2022-07-30

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Authors:

Magriotis, Plato A.

Scott, Mary E.

Kim, Kee D.

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Article abstract of DOI:10.1016/0040-4039(91)80759-Y

A new method for the synthesis of enediynes is described based on stannylcupration of acetylene and certain activated alkynes, in situ reaction with 1-halo-1-alkynes, iododestannylation, and Pd(0)-catalyzed coupling with terminal alkynes.Key Words: Stanny

Full text of DOI:10.1016/0040-4039(91)80759-Y

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