Journal of Medicinal Chemistry p. 100 - 106 (1992)
Update date:2022-07-29
Topics:
Ator, Mark A.
Schmidt, Stanley J.
Adams, Jerry L.
Dolle, Roland E.
Kruse, Lawrence I.
Frey, Carrie L.
Barone, Janice M.
A series of side chain modified analogues of cholesterol and lanosterol (1-10) have been synthesized and evaluated as inhibitors of the Candida albicans Δ24-sterol methyltransferase. Two sterol substrate analogues 1 and 2 which contained a 24-t
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