Synthesis, antitumor activity, and structure-activity relationship of some 4H-pyrano[3,2-h]quinoline and 7H-pyrimido[4′,5′:6,5]pyrano[3,2-h] quinoline derivatives

Article abstract of DOI:10.1007/s00044-012-0142-7

Several 4H-pyrano[3,2-h]quinoline (3a-d, 4a, 7a,b, 9a-c, 10a,b, 11a,b, and 13a-c) and 7H-pyrimido[4′,5′:6,5]pyrano[3,2-h]quinoline derivatives (8a-c) were obtained by treatment of 8-hydroxyquinoline (1a) and 8-hydroxy-2-methylquinoline (1b) with α-cyano-p