Synthesis of Teleocidins A, B and Their Congeners. Part 2. Synthesis of Lyngbyatoxin A (Teleocidin A-1), Teleocidin A-2, Pendolmycin, and (R,E)- and (S,E)-7-(3,7,11-Trimethyl-1,6,10-dodecatrien-3-yl)-(-)-indolactams V

Article abstract of DOI:10.1016/S0040-4020(01)82398-X

Details of the synthesis method of the tumor promoters, lyngbyatoxin A (= teleocidin A-1) (1) and teleocidin A-2 (2) from (R)- and (S)-methyl N-<7-(3,7-dimethyl-1,6-octadien-3-yl)-4-indolyl>-N-methyl-L-valinate (3 and 4) are presented.Other titled compounds, 6, 7a, and 7b, were prepared analogously. Key words: alkaloid synthesis; lyngbyatoxin A, teleocidin A-2; pendolmycin; teleocidin analogs.