Enzyme-Catalyzed Formation of Chiral Monosubstituted Mixed Diesters and Half Esters of Malonic Acid in Organic Solvents

DOI: 10.1021/jo00030a004

Source and publish data:

Journal of Organic Chemistry p. 1063 - 1065 (1992)

Update date:2022-07-29

Topics:

Authors:

Gutman, Arie L.

Shapira, Michal

Boltanski, Aviv

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00030a004

Enzymes in organic solvents were used to develop a strategy for the formation of heretofore unknown chiral monosubstituted malonate diesters and half esters.This enzymatic approach is not feasible in aqueous solutions because the activated malonic hydrogen invariably undergoes fast exchange accompanied by racemization.

Full text of DOI:10.1021/jo00030a004

Products guided by the article

Product name:Propanedioic acid, methyl-, methyl phenylmethyl ester, (S)-

Cas No:138434-88-5

R&D Labs maybe for 138434-88-5

Anhui Eapearl Chemical Co., Ltd.

Contact:86-562-5858458

Address:358 South Huaihe Road
NOVASYNCS CO., LTD

Contact:0512-63006287

Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA
Suzhou ATL Chemical Co.,ltd

Contact:+86-0512-69209969

Address:Room 317,Lushan Road,Suzhou New District,Jiangsu Province,China.
NINGBO YINZHOU PRECISE COLOR CO.,LTD.

Contact:86-574-88139809 86-574-83033159

Address:Qiming Road,Yinzhou,Ningbo,China
Langchem

Contact:+86+21-58956006 15800617331

Address:402 Room, 150# Cailun Road, Zhangjiang high tech park, Shanghai

Relevant to this article

Synthetic routes to ninhydrins. Preparation of ninhydrin, 5-methoxyninhydrin, and 5-(methylthio)ninhydrin

Doi:10.1080/00397919108055457
(1991)
Synthesis, structural characterization, and properties of some functionalized phosphine-containing diiron complexes as models for the active site of [FeFe]-hydrogenases

Doi:10.1021/om300418z
(2012)
Synthesis of β-Glycosyl amides from N-glycosyl dinitrobenzenesulfonamides

Doi:10.1080/07328303.2012.663431
(2012)
Cysteinoyl- and Cysteine-containing Dipeptidoylbenzotriazoles with Free Sulfhydryl Groups: Easy Access to N-terminal and Internal Cysteine Peptides

Doi:10.1111/j.1747-0285.2011.01303.x
(2012)
A one-step C-linked disaccharide synthesis from carbohydrate allylsilanes and tri-O-acetyl-D-glucal

Doi:10.1016/0008-6215(91)80009-C
(1991)
Discovery and modification of sulfur-containing heterocyclic pyrazoline derivatives as potential novel class of β-ketoacyl-acyl carrier protein synthase III (FabH) inhibitors

Doi:10.1016/j.bmcl.2012.05.091
(2012)

Article Doi