
Tetrahedron p. 3937 - 3942 (1983)
Update date:2022-08-03
Topics:
Beloeil, J. C.
Bertranne, M.
Fetizon, M.
Direct preparation of 14β-hydroxy steroids from 14α-H compounds is described; a 15β-hydroxy-14α-H compound is also obtained.Grignard reagents react with 14β-hydroxy-androstan-17-one in the "normal way", giving a 17β-side chain, but surprisingly organolithium reagents give the unexpected 17α-side chain.
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