Reactivity of 3,6-Dimethoxy-3,6-dimethylcyclohexa-1,4-diene (Part 3). Regioselective α-Arylation of Ketones via their Silyl Enol Ethers

Article abstract of DOI:10.1016/S0040-4020(01)86514-5

The reaction of 3,6-dimethoxy-3,6-dimethylcyclohexa-1,4-diene (1) with an excess of different silyl enol ethers derived from ketones in the presence of zinc dichloride leads to the corresponding ketones regioselectively arylated at the α position.