Tandem one-pot construction of indoles via palladium and copper-catalyzed coupling reactions of the blaise reaction intermediate

DOI: 10.1055/s-0031-1289753

Source and publish data:

Synthesis p. 1464 - 1476 (2012)

Update date:2022-09-26

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Authors:

Kim, Ju Hyun

Lee, Sang-Gi

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Article abstract of DOI:10.1055/s-0031-1289753

The palladium-catalyzed intramolecular N-arylation of the Blaise reaction intermediate, formed by reaction of nitriles with an in situ generated Reformatsky reagent from ethyl -bromo - (2-bromophenyl)acetate and zinc, afforded indoles in good yields. Exte

Full text of DOI:10.1055/s-0031-1289753

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