Synthesis of C-3 halogene-substituted apocodeines and apomorphines

Article abstract of DOI:10.1080/00397919108021590

A new effective method has been elaborated for the preparation of the hitherto unknown C-3 halogene derivatives (Cl, Br) of apocodeine and apomorphine, as well as of their N-demethyl-N-substituted (N-propyl, N-alkyl) analogues. These compounds are expected to possess an effect on the dopamine receptor system.