Stereoselective Synthesis of Both Diastereomers of the α-Methyl-β-hydroxy-β-alkyl(aryl) Units by Use of Tin(II) Triflate-Mediated Aldol Reaction

DOI: 10.1021/jo00031a004

Source and publish data:

Journal of Organic Chemistry p. 1324 - 1326 (1992)

Update date:2022-08-04

Topics:

Authors:

Kobayashi, Shu

Hachiya, Iwao

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Article abstract of DOI:10.1021/jo00031a004

Both diastereomers of the α-methyl-β-hydroxy-β-alkyl(aryl) units are prepared by the tin(II) triflate-mediated aldol reaction of 1-(ethylthio)-1-(trimethylsiloxy)propene with α-keto esters in high selectivities.

Full text of DOI:10.1021/jo00031a004

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