Helvetica Chimica Acta p. 1697 - 1706 (1991)
Update date:2022-08-04
Topics:
Lebeau, Luc
Oudet, Pierre
Mioskowski, Charles
The synthesis of phospholipids 1n-3n, rationally designed for two-dimensional crystallization of progesterone and estradiol receptors, is reported.The structure of theses lipids provides them with essential properties such as fluidity and stability when spread into monolayers at the air/H2O interface, affinity for the protein to be crystallized, and accessibility of the ligand under the lipid monolayer.
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