Journal of Chemical Sciences p. 129 - 139 (2013)
Update date:2022-09-26
Topics:
Kumar, Shiv
Kumar, Nitin
Drabu, Sushma
Minhaj, Md. Akram
Twelve compounds belonging to series N-[3-chloro-2-oxo-4-(substituted) phenylazetidin-1-yl]-2-(3-methyl-2-oxoquinoxalin-1(2H)-yl)acetamide (5a-l) were synthesized. These compounds were evaluated for their in vitro antibacterial against E. coli, S. aureus, K. pneumoniae, P. aeruginosa and antifungal activity against C. albicans, A. niger and A. flavus by cup-plate method. Structures of all the newly synthesized compounds were confirmed by their spectral data interpretation. Compound 5g having p-dimethylaminophenyl group on 4-position of azetidinone ring attached to N-atom of acetamido group on 1-position of 3-methyl-1H-quinoxaline-2-one, was found to be active against all the bacterial and fungal strains under investigation.
View MoreContact:+86-571-87010026
Address:202, Zhenhua Road,
Shangyu Sanhechemicals Co.,LTD.
Contact:86-0571-56696839
Address:Num.2952,Nanhuan Road,Binjiang District,Hangzhou,China
Wuxi Highness Chemical Co.,Ltd
website:https://www.phtpharmatech.com/
Contact:86-510-81771080
Address:No58 East Xinguan Rd, Guanlin Town, Yixing City, Jiangsu China
Zibo Xiaoguang Chemical Material Co., Ltd
Contact:15954099116
Address:Boshan Development Zone
Contact:86-310-8067016
Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
Doi:10.1016/j.jfluchem.2003.12.015
(2004)Doi:10.1039/c2ob25685a
(2012)Doi:10.1002/ejoc.201301718
(2014)Doi:10.1002/ejoc.201200180
(2012)Doi:10.1007/s12039-011-0138-8
(2011)Doi:10.1039/c2dt30448a
(2012)