Ring transformation with bridged 1,3-dicarbonyl heteroanalogues, III. 5-(ω-aminoalkyl)-1,2,4-oxadiazoles by ring-transformations of 3-methylthio-2-aza-3-propeniminium salts

DOI: 10.1002/ardp.2503241205

Source and publish data:

Archiv der Pharmazie p. 963 - 965 (1991)

Update date:2022-08-04

Topics: Experimental terms Ring transformation

Authors:

Patzel Patzel

Liebscher

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Article abstract of DOI:10.1002/ardp.2503241205

3-Methylthio-2-aza-3-propeniminium salts 5 react with hydroxylamine after ring transformation under formation of 5-(ω-aminoalkyl)-1,2,4-oxadiazole hydroiodides 4·HI, which show a remarkable antitussive activity.

Full text of DOI:10.1002/ardp.2503241205

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Product name:[5-(3-Methylamino-propyl)-[1,2,4]oxadiazol-3-yl]-phenyl-amine; hydriodide

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