Synthetic Approaches to the Axane Family of Sesquiterpenoids. Total Synthesis of dl-Axamide-4, dl-Axisonitrile-4, and dl-Axisothiocyanate-4

Article abstract of DOI:10.1021/jo00033a023

Two methods for the preparation of perhydroindan 7 are described.One involves an intramolecular free radical cyclization in a key step and proceeds in 13 steps and 9percent yield from anisole (9).The other involves an intramolecular conjugate addition med