A new approach to the synthesis of neuraminic acid analogues

DOI: 10.1016/0040-4039(91)85030-9

Source and publish data:

Tetrahedron Letters p. 7025 - 7028 (1991)

Update date:2022-08-04

Topics:

Authors:

Vlahov, Ioncho R.

Vlahova, Petinka I.

Schmidt, Richard R.

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Article abstract of DOI:10.1016/0040-4039(91)85030-9

2-Alkoxy acrylate derivatives 8 and 11, readily prepared from D-glucono-1,5-lactone by ring opening and β-elimination, are converted into neuraminic acid analogues 9 and 12 via debenzylation and spontaneous cyclization or ring closure via oxymercuration-demercuration, respectively.

Full text of DOI:10.1016/0040-4039(91)85030-9

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