The highly enantioselective addition of indoles and pyrroles to isatins-derived N-Boc ketimines catalyzed by chiral phosphoric acids

DOI: 10.1039/c2cc33200k

Source and publish data:

Chemical Communications p. 8003 - 8005 (2012)

Update date:2022-08-15

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Authors:

Feng, Jingchao

Yan, Wenjin

Wang, Dong

Li, Peng

Sun, Quantao

Wang, Rui

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Article abstract of DOI:10.1039/c2cc33200k

The first asymmetric aza-Friedel-Crafts reaction of indoles and pyrroles with isatin-derived N-Boc ketimines catalyzed by chiral phosphoric acids is reported. In general, derivatives of substituted 3-amino-2-oxindoles were obtained with excellent enantios

Full text of DOI:10.1039/c2cc33200k

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