Synthesis of Ψ[CH(CN)NH] pseudopeptides. A new peptide bond surrogate

DOI: 10.1016/0040-4039(91)80539-I

Source and publish data:

Tetrahedron Letters p. 7579 - 7582 (1991)

Update date:2022-07-30

Topics:

Authors:

Herranz, Rosario

Suarez-Gea, M. Luisa

Vinuesa, Soledad

Garcia-Lopez, M. Teresa

Martinez, Ana

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Article abstract of DOI:10.1016/0040-4039(91)80539-I

An easy and versatile general method for the preparation of the new peptide bond surrogate Ψ[CH (CN)NH], by the Lewis acid catalyzed reaction of N-protected α-amino aldehydes with a C-protected amino acid or peptide in the presence of TMSCN, is described.

Full text of DOI:10.1016/0040-4039(91)80539-I

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