Synthese von α-Fluoracrylsaeure und Derivaten

Article abstract of DOI:10.1016/S0022-1139(00)80116-5

Three new routes to derivatives of α-fluoracrylic acid, including a laboratory synthesis and a large-scale method, are reported.The processes are (i) addition of elementary fluorine to acrylic esters and subsequent elimination of HF; (ii) addition of difluorocarbene to isopropenyl methyl ether, oxidation via ring opening and dehalogenation; and (iii) "nitrofluorination" of 2,3-dichloropropene, hydrolysis and dechlorination.