Asymmetric hydrogenation of thiophenes and benzothiophenes

DOI: 10.1021/ja306622y

Source and publish data:

Journal of the American Chemical Society p. 15241 - 15244 (2012)

Update date:2022-08-03

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Authors:

Urban, Slawomir

Beiring, Bernhard

Ortega, Nuria

Paul, Daniel

Glorius, Frank

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Article abstract of DOI:10.1021/ja306622y

An efficient and highly asymmetric ruthenium-N-heterocyclic carbene-catalyzed hydrogenation of substituted thiophenes and benzothiophenes is described, providing a new strategy for the formation of valuable enantiomerically pure tetrahydrothiophenes and 2,3-dihydrobenzothiophenes.

Full text of DOI:10.1021/ja306622y

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