An efficient asymmetric biomimetic transamination of α-keto esters to chiral α-amino esters

Article abstract of DOI:10.1021/ol302427d

An efficient asymmetric biomimetic transamination of α-keto esters with quinine derivatives as chiral bases was described. A wide variety of α-amino esters containing various functional groups can be synthesized in high yield and enantioselectivity.