New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b] quinoline as cytotoxic DNA topoisomerase II inhibitors

DOI: 10.1016/j.bmcl.2012.08.032

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 6103 - 6107 (2012)

Update date:2022-08-04

Topics:

Authors:

Luniewski, Wojciech

Wietrzyk, Joanna

Godlewska, Joanna

Switalska, Marta

Piskozub, Malgorzata

Peczynska-Czoch, Wanda

Kaczmarek, Lukasz

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Article abstract of DOI:10.1016/j.bmcl.2012.08.032

Novel indolo[2,3-b]quinoline derivatives substituted at N-6 and C-2 or C-9 positions with (dimethylamino)ethyl chains linked to heteroaromatic core by ether, amide or amine bonds, were manufactured and evaluated in vitro for their cytotoxic activity again

Full text of DOI:10.1016/j.bmcl.2012.08.032

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