A CONVENIENT METHOD FOR THE SYNTHESIS OF (E)-3-ALKENOIC ACIDS BY A REGIO- AND STEREOSELECTIVE REACTION OF β-VINYL-β-PROPIOLACTONE WITH ORGANOCOPPER REAGENTS

Article abstract of DOI:10.1016/S0040-4039(01)90448-4

β-Vinyl-β-propiolactone reacts regio- and stereoselectively with Grignard reagents in the presence of copper(I) catalyst or with diorganocuprates to afford (E)-3-alkenoic acids in high yields.