Chemical and Pharmaceutical Bulletin p. 122 - 126 (1992)
Update date:2022-08-05
Topics:
Iwasaki
Yamazaki
Nishitani
Kondo
Sato
A series of 2-aminoethanol derivatives was synthesized and their inhibitory activities against protein kinase C were investigated. Among these compounds, 2-endo-hexadecylamino-5-norbornene-2-exo-methanol (4h) and 2-endohexadecylamino-5-norbornene-2,3-exo-dimethanol (4i) inhibited protein kinase C at the IC50 values of 2 x 10-5 and 1 x 10-5 M, respectively, but not protein kinase A at a concentration of 1 x 10-3 M. The structure-activity relationships are discussed.
View Morewebsite:http://www.maisonchem.com.cn
Contact:0086-311-83833777
Address:Leitou industrial district, xinji, shijiazhuang city, hebei province,
Puyang Huicheng Electronic Material Co., Ltd
website:http://huichengchem.weba.testwebsite.cn/index_en.html
Contact:+86-393-8910800
Address:West Section Shengli Road, Puyang457000, China
Shanghai Sunwise Chemical Co., Ltd
website:http://www.sunwisechem.com
Contact:86-021-33883180
Address:Room 10E, Building G, Westlink Center, No. 2337 Gudai Road, Minhang District, Shanghai, China PC: 201100
Chongqing Changfeng Chemical Co., Ltd.
website:http://www.changfengchem.com
Contact:+86-23-67896333
Address:30th Floor, Longhu Ziduxingzuo Building A, 1st Branch,YuSong Rd., Yubei District, Chongqing, China
Nanjing Vincero International Trading Co.,Ltd
Contact:8618936897229
Address:NO.68, ZhuShan Road, JiangNing WanDa Plaza, Building E Room 1703
Doi:10.1002/poc.2939
(2012)Doi:10.1016/j.tet.2015.05.110
(2015)Doi:10.1039/c5dt02226f
(2015)Doi:10.1080/10426500701758421
(2008)Doi:10.2298/JSC111001023J
(2012)Doi:10.1021/jm00074a007
(1993)
