Synthesis and physicochemical properties of alternating α,β-oligodeoxyribonucleotides with alternating (3' → 3')- and (5' → 5')-internucleotide phosphodiester linkages

Article abstract of DOI:10.1021/jo00111a009

A simple and straightforward synthesis of α-2'-deoxycytidine and α-2'-deoxyadenosine derivatives 6a,b has been achieved from commercial N⁴-benzoyl-b-2'-deoxycytidine and N⁶-benzoyl-β-2'deoxyadenosine, respectively. Properly protected