Synthesis and properties of D-glucosamine N-peptidyl derivatives as substrate analog inhibitors of papain and cathepsin B

DOI: 10.1016/0223-5234(91)90001-4

Source and publish data:

European Journal of Medicinal Chemistry p. 753 - 762 (1991)

Update date:2022-08-05

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Authors:

Giordano, C

Gallina, C

Consalvi, V

Scandurra, R

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Article abstract of DOI:10.1016/0223-5234(91)90001-4

N-peptidyl derivatives of D-glucosamine 7c-7n were synthesized and tested as reversible, substrate analog inhibitors of cysteine and serine-proteases.D-glucosamine itself showed fair inhibiting properties against cysteine-proteases.Derivatives 7c-7i, desi

Full text of DOI:10.1016/0223-5234(91)90001-4

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