Structure-activity relationship study of TXA2 receptor antagonists. 4- [2-(4-Substituted phenylsulfonylamino)ethylthio]phenoxyacetic acids and related compounds

DOI: 10.1248/cpb.43.1132

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1132 - 1136 (1995)

Update date:2022-08-04

Topics:

Authors:

Kawashima

Sato Sato

Yamamoto

Shimazaki

Chiba Chiba

Satake Satake

Iwata Iwata

Hatayama

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Article abstract of DOI:10.1248/cpb.43.1132

We have recently reported that 4-[2-(4-substituted phenylsulfonylamino)ethylthio]phenoxyacetic acids and related compounds showed potent thromboxane A₂ (TXA₂) receptor antagonist activity. To understand how substituents affect the bi

Full text of DOI:10.1248/cpb.43.1132

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