Synthesis, pharmacological characterization, and structure - Activity relationship studies of small molecular agonists for the orphan GPR88 receptor

DOI: 10.1021/cn500082p

Source and publish data:

ACS Chemical Neuroscience p. 576 - 587 (2014)

Update date:2022-07-29

Topics:

Authors:

Jin, Chunyang

Decker, Ann M.

Huang, Xi-Ping

Gilmour, Brian P.

Blough, Bruce E.

Roth, Bryan L.

Hu, Yang

Gill, Joseph B.

Zhang, X. Peter

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Article abstract of DOI:10.1021/cn500082p

GPR88 is an orphan G-protein-coupled receptor (GPCR) enriched in the striatum. Genetic deletion and gene expression studies have suggested that GPR88 plays an important role in the regulation of striatal functions and is implicated in psychiatric disorder

Full text of DOI:10.1021/cn500082p

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