Journal of the Chemical Society. Chemical communications p. 437 - 439 (1992)
Update date:2022-09-26
Topics:
Nagao, Yoshimitsu
Matsunaga, Hiroshi
Kumagai, Toshio
Inoue, Yoshinori
Miwa, Yoshihisa
Taga, Tooru
The asymmetric total synthesis of thienamycin-like γ-lactam 1 and its analogue 2 has been accomplished by utilising highly diastereoselective alkylation of tin(II) enolate 5 on acyl imine obtained in situ from chiral 3-substituted 5-acetoxypyrrolidin-2-on
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