Synthesis and Structure Determination of (3S,5S)-2,3,5,6-Tetrahydro-3,5-dialkyl-N-(tert-butyloxycarbonyl)-4H-1,4-oxazine-2-ones

Article abstract of DOI:10.1016/S0040-4039(00)91677-0

(5S)-2,3,5,6-Tetrahydro-5-alkyl-N-(tert-butyloxycarbonyl)-4H-1,4-oxazine-2-ones, which are readily prepared from optically pure 2-amino alcohols alkylate selectively at the C-3 position to give (3S,5S)-dialkyl-2,3,5,6-tetrahydro-5-alkyl-N-(tert-butyloxyca