Synthesis of some new (2(1H)-pyridones from 3-amino-3-(dialkylamino)propenenitriles

DOI: 10.1055/s-1992-26113

Source and publish data:

Synthesis p. 371 - 373 (1992)

Update date:2022-09-26

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Authors:

Cocco Cocco

Congiu Congiu

Maccioni

Onnis Onnis

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Article abstract of DOI:10.1055/s-1992-26113

3-Amino-3-(dialkylamino)propenenitriles were reacted with acetylenecarboxylates to give 2(1H)-pyridone derivatives. The reaction with ethyl propynate afforded dienamino ester intermediates which cyclized in sodium ethoxide/ethanol to 5-cyano-2(1H)-pyridon

Full text of DOI:10.1055/s-1992-26113

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Product name:1-Piperazinecarboxylic acid, 4-[3-cyano-4-(ethoxycarbonyl)-1,6-dihydro-6-oxo-2-pyridinyl]-, ethyl ester

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