Organic Letters p. 362 - 365 (2013)
Update date:2022-08-05
Topics: Solvent Microwave reactor
Nguyen, Huy H.
Kurth, Mark J.
A variety of N-aryl β-nitroenamines were effectively transformed into 3-nitroindoles in good yields and with complete regioselectivity via a rapid microwave (μW) assisted intramolecular arene-alkene coupling reaction. This report further demonstrates the versatility of this method by constructing 3-carboalkoxy-and 3-cyanoindoles. Optimization data, substrate scope, and applications are discussed.
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(2013)
