Synthesis and antiviral evaluation of analogs of adenosine-N1-oxide and 1-(benzyloxy)adenosine

Article abstract of DOI:10.1080/07328319808003478

The activity of a series of compounds related to adenosine-N¹-oxide (1) and 1-(benzyloxy)adenosine (42) against vaccinia virus has been determined both in vitro and in a vaccinia mouse tailpox model. Significant activities have been found both in vitro and in vivo for a number of the synthetic compounds.

Full text of DOI:10.1080/07328319808003478

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Nucleosides and Nucleotides
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Synthesis and Antiviral Evaluation of
Analogs of Adenosine-N 1-Oxide and 1-
(Benzyloxy)Adenosine
Cecil D. Kwong a , Charles A. Krauth a , Anita T. Shortnacy-Fowler a
,
Gussie Arnett a , Melinda G. Hollingshead a , William M. Shannon a
John A. Montgomery a & John A. Secrist III a
a Southern Research Institute , Birmingham, Alabama, 35255–5305
Published online: 21 Aug 2006.
,
To cite this article: Cecil D. Kwong , Charles A. Krauth , Anita T. Shortnacy-Fowler , Gussie Arnett ,
Melinda G. Hollingshead , William M. Shannon , John A. Montgomery & John A. Secrist III (1998)
Synthesis and Antiviral Evaluation of Analogs of Adenosine-N 1-Oxide and 1-(Benzyloxy)Adenosine,
Nucleosides and Nucleotides, 17:8, 1409-1443, DOI: 10.1080/07328319808003478
To link to this article: http://dx.doi.org/10.1080/07328319808003478
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